UGUSTA, Ga. (Dec. 6, 2017) – In an exciting breakthrough scientists have discovered that a common pain medication often prescribed for chronic pain can help preserve vision in a model of severe, blinding retinal degeneration. The vision preservation could activate one of the most powerful antioxidants in the human body known as Nrf2. This targets… Continue reading Augusta University Discovers How Nrf2 Activator Preserves Sight in Retinal Degeneration Model
Tag: NRF2
Reversal of persistent fibrosis in aging by targeting nox4-Nrf2 redox imbalance – Sciencemag.org
A brand new article in Sciencemag.org presents a study demonstrating how pathological fibrosis increases with age, but how NRF2 activation in mice was able to reverse the damage and repair lung capacity and fibrosis (scar tissue) resolution. This is a promising study because the current treatments of pathological and cystic fibrosis are costly and very… Continue reading Reversal of persistent fibrosis in aging by targeting nox4-Nrf2 redox imbalance – Sciencemag.org
A New Nrf2 and Diabetes Study Underway
The American Diabetes Journal has details on an interesting NRF2 study currently in progress. Diabetes is a huge concern to many individuals and families. According to statistics published by the American Diabetes Association more than 25.8 million children and adults in the United States in 2010 have diabetes. That accounts for 8.3% of the population.… Continue reading A New Nrf2 and Diabetes Study Underway
Review: Nrf2, a multi-organ protector?
A classic NRF2 study entitled, “Nrf2, a multi-organ protector?” predates many of the latest studies regarding NRF2. It was however one of those landmark studies that paved the way for later studies. The study states, “Nrf2 may serve as a master regulator of the ARE-driven cellular defense system against oxidative stress.” and then goes on… Continue reading Review: Nrf2, a multi-organ protector?
Tecfidera (BG-12) Nrf2 Activator Approved by FDA for Multiple Sclerosis (MS) Treatment
Although there is no treatment that will cure Multiple Sclerosis, there are three oral medications approved by the FDA to be a first-line treatment to slow down the progression of the disease. Dimethyl Fumarate (Tecfidera, Biogen Idec) joins fingolimod (Gilenya) and teriflunomide (Aubagio) as the new “kid on the block”. It is specifically approved for… Continue reading Tecfidera (BG-12) Nrf2 Activator Approved by FDA for Multiple Sclerosis (MS) Treatment
Could a Nrf2 Activator Stimulate Neuro Protection in Neurodegenerative Diseases?
What are Neurodegenerative diseases? Neurological diseases are defined as disorders to the central and peripheral nervous systems including, but not limited to the brain, spinal chord, nerves and muscles. These diseases can result in neuro damage including nerve or cell death. Studies are underway to determine how effective NRF2 activation could be in preventing damage… Continue reading Could a Nrf2 Activator Stimulate Neuro Protection in Neurodegenerative Diseases?
Fibromyalgia, Oxidative Stress and Nrf2 – Any Hope?
Before jumping into the impact of Nrf2 activation on Fibromyalgia and it potential benefits, let’s review a few common facts about the illness. What is Fibromyalgia? Fibromyalgia is a relatively common condition in which an individual experiences pain and discomfort throughout the body. Side effects of this pain are anxiety, lack of sleep, headaches, fatigue… Continue reading Fibromyalgia, Oxidative Stress and Nrf2 – Any Hope?