Oxidative Stress

Retraction notice to"The synergistic administration of sanguinarine and curcumin ameliorates indomethacin-induced small intestinal injury in rats through the modulation of Nrf2 and NF-κB signaling pathways" [Biochem. Biophys. Res. Commun. 781 (2025) 152551].

Biochemical and biophysical research communications 2026-May-01

Lin Xiulian, Zhou Yuanjiao, Xia Li, Chen Menghan, Liao Wenjing, Yang Xuefeng, Tuo Qinhui, Lin Limei, Liao Duanfang, Zeng Jianguo

Abstract

Key Findings

The study investigated the combined effects of sanguinarine and curcumin on indomethacin-induced small intestinal injury in rats.
The therapeutic effects were proposed to be mediated through modulation of Nrf2 and NF-κB signaling pathways.
The article has been retracted, indicating that the findings are no longer considered reliable.

Clinical Significance

Although the study initially suggested a potential therapeutic approach for intestinal injury via oxidative stress pathways, the retraction undermines its clinical applicability and calls for further validated research.

Citation

Lin Xiulian, Zhou Yuanjiao, Xia Liet al.. Retraction notice to"The synergistic administration of sanguinarine and curcumin ameliorates indomethacin-induced small intestinal injury in rats through the modulation of Nrf2 and NF-κB signaling pathways" [Biochem. Biophys. Res. Commun. 781 (2025) 152551]. Biochemical and biophysical research communications. 2026-May-01.

DOI: 10.1016/j.bbrc.2026.153861