RETRACTED: Das et al. Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-β1/Smad/Collagen IV Signalling.
Das Sonjit, Dewanjee Saikat, Dua Tarun K, Joardar Swarnalata, Chakraborty Pratik, Bhowmick Shovonlal, Saha Achintya, Bhattacharjee Simanta, De Feo Vincenzo
Abstract
The journal retracts the article titled "Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-β1/Smad/Collagen IV Signalling" [...].
Key Findings
- Carnosic acid was reported to attenuate cadmium-induced nephrotoxicity
- The mechanism involved inhibition of oxidative stress
- Promotion of Nrf2/HO-1 signaling and impairment of TGF-β1/Smad/Collagen IV signaling were implicated
Clinical Significance
Although the study was retracted, the findings initially suggested that targeting oxidative stress pathways via Nrf2/HO-1 signaling could be a potential therapeutic approach for cadmium-induced kidney damage.
Citation
Das Sonjit, Dewanjee Saikat, Dua Tarun Ket al.. RETRACTED: Das et al. Carnosic Acid Attenuates Cadmium Induced Nephrotoxicity by Inhibiting Oxidative Stress, Promoting Nrf2/HO-1 Signalling and Impairing TGF-β1/Smad/Collagen IV Signalling. Molecules (Basel, Switzerland). 2026-Sep-18.