Oxidative Stress
Corrigendum to "VSMC-derived 3HAA activates AhR to drive abdominal aortic aneurysm formation via the p62-Nrf2 axis" [Redox Biol. 95, (2026), 104256].
Redox biology 2026-Nov
Ramprasath Tharmarajan, Han Young-Min, Ding Ye, Carr Sean Michael, Zou Ming-Hui
Abstract
Key Findings
- VSMC-derived 3HAA activates AhR receptor
- Activation of AhR drives abdominal aortic aneurysm formation
- The mechanism involves the p62-Nrf2 signaling axis
Clinical Significance
Understanding the p62-Nrf2 axis in aneurysm formation may guide development of targeted therapies to prevent or treat abdominal aortic aneurysms by modulating oxidative stress pathways.
Citation
Ramprasath Tharmarajan, Han Young-Min, Ding Yeet al.. Corrigendum to "VSMC-derived 3HAA activates AhR to drive abdominal aortic aneurysm formation via the p62-Nrf2 axis" [Redox Biol. 95, (2026), 104256]. Redox biology. 2026-Nov.
DOI: 10.1016/j.redox.2026.104428